Potential Hyperglycemia In Type 2 Diabetes Mellitus Patients Due To Drug Interactions At Hospital
DOI:
https://doi.org/10.36858/ipj.v1i2.19Keywords:
diaebetes mellitus, drug interactions, hyperglycemiaAbstract
Background: Hyperglycemia is a medical condition in the form of an increase in blood glucose levels beyond normal limits with a blood sugar concentration of ≥200 mg/dl. Hyperglycemia that is not well controlled can cause serious disorders of the body's systems, especially the nerves and blood vessels. Based on WHO data, the prevalence of type 2 DM with the potential for hyperglycemia in the world in 2019 was 5.3%. This figure is expected to increase to 6.3% in 2030.
Objective: This research was conducted to determine the potential for hyperglycemia in type 2 diabetes mellitus patients due to drug interactions at one of hospital in Jember.
Method: This research uses a quantitative design with retrospective data collection, namely research obtained based on information from patient medical records. The population in this study was 539 patients suffering from type 2 diabetes mellitus for the period January-December 2022. The sample from this study was type 2 diabetes mellitus patients who met the inclusion criteria. Sampling was calculated using the Slovin formula using random sampling techniques and the results obtained were 84 medical record samples. Analysis using univariate. Data is displayed in frequency and percentage form. Data processing uses Microsoft Excel and SPSS.
Results: Most of the drugs received by type 2 diabetes mellitus patients experienced interactions that had the potential to cause hyperglycemia with blood sugar levels ≥200 mg/dl (96.43%) and a moderate clinical significance level of 70.24%.
Conclusion: There is a potential for hyperglycemia caused by diabetes drug interactions. Monitoring drug interactions and effective treatment in patients with type 2 diabetes mellitus needs to be carried out to achieve optimal therapy targets and increase awareness of healthy lifestyles in diabetes management.
References
Hartanti, Pudjibudojo JK, Aditama L, Rahayu RP. Pencegahan dan Penanganan Diabetes Mellitus. Fak Psikol Univ Surabaya. 2019;1–96.
Norma Lalla NS, Rumatiga J. Ketikdakstabilan Kadar Glukosa Darah Pada Pasien Diabetes Melitus Tipe II. J Ilm Kesehat Sandi Husada. 2022;11:473–9.
Dasopang ES, Harahap U, Lindarto D. Polipharmacy and Drug Interactions in Elderly Patients with Metabolic Diseases. Indones J Clin Pharm. 2020;4(4):235–41.
Fauziah H, Mulyana R, Martini RD. Polifarmasi Pada Pasien Geriatri. Hum Care J. 2020;5(3):804.
Saibi Y, Hasan D, Safitri B, Anwar VA. Potensi Hipoglikemia Dan Hiperglikemia Pada Pasien Diabetes Melitus Tipe 2 Akibat Interaksi Obat. J Ilm Ibnu Sina Ilmu Farm dan Kesehat. 2020;5(2):258–67.
Ramatillah DL. Buku interaksi obat. Fak Farm. 2020;1–67.
Zaini Miftach. Perbedaan Kadar Gula Darah Pada Penderita Diabetes Melitus Tipe 2 Di Puskesmas Jember Kidul Setelah Pemberian Minuman Cokelat. 2020;2:53–4.
Prasetyawan F, S. Mayasari. Buku Manajemen Farmasi [internet]. PT Penamuda Media; 2024. 146–161 p. Available from: https;//anyflip.com/tdezn/xgoh/basic
Kementerian Kementerian Kesehatan Republik Indonesia. (2016).
Aulia G, Dwi Pratiwi R, Dhini Soleha A. Gambaran Interaksi Obat Antidiabetik Oral Pada Peresepan Pasien Dewasa Diabetes Mellitus Rawat Jalan Di Rumah Sakit Aqidah Kota Tangerang Description of Oral Antidiabetic Medicine Interactions Administration of Adult Patients Diabetes Mellitus Treatment i. 2020;1(1):892.
Saibi Y, Hasan D, Shaqila V. Potensi Interaksi Obat pada Pasien Diabetes Melitus Tipe 2 di Rumah Sakit X Tangerang Selatan. 2021;8(3):100–4.
Suryati. Bab 1 pendahuluan. Pelayanan Kesehat. 2019;(2015):3–13.
Herdiani FD. Penerapan Oracle Enterprise Architecture Development (OADP) Dalam Perancangan Arsitektur Sistem Informasi Manajemen Aset Properti: Studi Kasus PT. Pos Properti Indonesia. J Ilm Ilmu Terap Univ Jambi. 2021;5(1):31–8. 14. Gunawan S, Rahmawati R. Hubungan Usia, Jenis Kelamin dan Hipertensi dengan Kejadian Diabetes Mellitus Tipe 2 di Puskesmas Tugu Kecamatan Cimanggis Kota Depok Tahun 2019. ARKESMAS (Arsip Kesehat Masyarakat). 2021;6(1):15–22.
Kesehatan J, Faktor A, Mempengaruhi Y, Neuropati K. Viva medika. 12.
Pibriyanti K, Hidayati KN. Anak perempuan dan obesitas sebagai faktor risiko kejadian kadar gula darah tinggi pada anak sekolah dasar. J Gizi Indones (The Indones J Nutr. 2018;6(2):90–3.
Isnaini N, Ratnasari R. Faktor risiko mempengaruhi kejadian Diabetes mellitus tipe dua. J Kebidanan dan Keperawatan Aisyiyah. 2018;14(1):59–68.
Rosita R, Kusumaningtiar DA, Irfandi A, Ayu IM. Hubungan Antara Jenis Kelamin, Umur, Dan Aktivitas Fisik Dengan Diabetes Melitus Tipe 2 Pada Lansia Di Puskesmas Balaraja Kabupaten Tangerang. J Kesehat Masy. 2022;10(3):364–71.
Ussa rikma eliyana. Hubungan Interaksi Antar Obat Terhadap Kadar Gula Darah Pada Pasien Diabetes Rawat Inap Di Rumah Sakit Islam Sultan Agung Semarang Periode 2020. 2021. 1–116 p.
Betteng R. Analisis Faktor Resiko Penyebab Terjadinya Diabetes Melitus Tipe 2 Pada Wanita Usia Produktif Dipuskesmas Wawonasa. J e-Biomedik. 2014;2
Mayasari, S. (2020). Analysis Of The Used Of Captopril Drug With Blood Pressure Of Hypertension Patients. Jurnal Kesehatan Dr. Soebandi, 8(2), 123–127. https://doi.org/10.36858/jkds.v8i2.225
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